金沙游戏官网(中国)有限公司

2018.08 至今            金沙游戏官网，教授

2016.03--2018.07    集团公司食品科学与工程学院，教授

2016.09--2017.09    美国普渡大学Whistler碳水化合物研究中心国家公派访问学者

2012.12--2016.02    集团公司生物与食品工程学院，教授

2009.11--2012.11    集团公司生物与食品工程学院，副教授

2007.09--2009.11    江南大学轻工技术与工程博士后科研流动站，博士后

（1）农产品精深加工及副产物综合利用

（2）食品营养与功能

（3）天然活性物质研究与开发

1. 国家自然科学基金面上项目“食用仙人掌果多糖调控胰岛beta细胞氧化应激的结构基础及作用机理研究”（项目编号：31972977，2020.1-2023.12）（主持人）

2. “十三五”国家重点研发计划“现代食品加工及粮食收储运技术与装备”重点专项2017年度项目“食品绿色节能制造关键技术及装备研发”课题“高效节能的食品加工装备智能化及组合应用”（课题编号：2017YFD0400405，2017.7-2020.12）（子课题负责人）

3. 2016年安徽省科技重大专项项目“小麦淀粉系列产品开发关键技术研究及产业化示范”（项目编号：16030701079，2016.9-2018.12）（合作单位负责人）

4. 国家自然科学基金面上项目“鹰嘴豆异黄酮对炎症介导的多巴胺能神经元损伤的保护作用及机制研究”（项目编号：31171650，2012.1-2015.12）（主持人）

5. 国家自然科学基金青年基金项目“淀粉基微凝胶包β-胡萝卜素纳米乳液体系的构建及靶向控释机理研究”（项目编号：31601429，2017.01-2019.12）（排名第二）

安徽省自然科学基金项目“淀粉基β-胡萝卜素微凝胶载体的形成及控释机理研究”（项目编号：1708085QC78，2017.07-2019.06）（排名第二）

近年来在食品学科国际主流期刊发表高质量论文70余篇，其中以第一作者和通讯作者在Food Chemistry、Food Hydrocolloids、Carbohydrate Polymers等期刊发表论文近50篇。

代表性论文：

1. Qin Yang, Ya-Ru Wang, Yi-Jing Li-Sha, Han-Qing Chen*. Physicochemical, structural and gelation properties of arachin-basil seed gum composite gels: Effects of salt types and concentrations. Food Hydrocolloids, 2021, 113: 106545.

2. Qin Yang, Ya-Ru Wang, Yi-Jing Li-Sha, Han-Qing Chen*. The effects of basil seed gum on the physicochemical and structural properties of arachin gel. Food Hydrocolloids, 2021, 110: 106189.

3. Ya-Ru Wang, Qin Yang, Yi-Jing Li-Sha, Han-Qing Chen*. Structural, gelation properties and microstructure of rice glutelin/sugar beet pectin composite gels: Effects of ionic strengths. Food Chemistry, 2021, 346, 128956. 

4. Qing-Qing Lv, Juan-Juan Cao, Rui Liu, Han-Qing Chen*. Structural characterization, α-amylase and α-glucosidase inhibitory activities of polysaccharides from wheat bran. Food Chemistry, 2021, 341: 128218.

5. Jin-Lei Fan, Ni Han, Han-Qing Chen*. Physicochemical and structural properties of wheat gluten/rice starch dough-like model. Journal of Cereal Science, 2021, 98: 103181.

6. Bo Chen, Ya-Ru Wang, Jin-Lei Fan, Qin Yang, Han-Qing Chen*. Effect of glutenin and gliadin modified by protein-glutaminase on retrogradation properties and digestibility of potato starch. Food Chemistry, 2019, 301: 125226.

7. Ya-Ru Wang, Qin Yang, Jin-Lei Fan, Bao Zhang, Han-Qing Chen*. The effects of phosphorylation modification on the structure, interactions and rheological properties of rice glutelin during heat treatment. Food Chemistry, 2019, 297: 124978.

8. Yi Pan, Zhengzong Wu, Bao Zhang*, Xiao-Min Li, Ran Meng, Han-Qing Chen*, Zheng-Yu Jin. Preparation and characterization of emulsion stabilized by octenyl succinic anhydride-modified dextrin for improving storage stability and curcumin encapsulation. Food Chemistry, 2019, 294: 326-332.

9. Meng-Na Li, Bao Zhang, Ying Xie, Han-Qing Chen*. Effects of debranching and repeated heat-moisture treatments on structure, physicochemical properties and in vitro digestibility of wheat starch. Food Chemistry, 2019, 294: 440-447.

10. Xiao-Min Li, Zheng-Zong Wu, Bao Zhang*, Yi Pan, Ran Meng, Han-Qing Chen*. Fabrication of chitosan hydrochloride and carboxymethyl starch complex nanogels as potential delivery vehicles for curcumin. Food Chemistry, 2019, 293: 197-203.

11. Ying Xie, Bao Zhang, Meng-Na Li, Han-Qing Chen*. Effects of cross-linking with sodium trimetaphosphate on structural and adsorptive properties of porous wheat starches. Food Chemistry, 2019, 289: 187-194.

12. Juan-Juan Cao, Qing-Qing Lv, Bao Zhang, Han-Qing Chen*. Structural characterization and hepatoprotective activities of polysaccharides from the leaves of Toona sinensis (A. Juss) Roem. Carbohydrate Polymers, 2019, 212: 89-101.

13. Bin-Hui Wang, Juan-Juan Cao, Bao Zhang, Han-Qing Chen*. Structural characterization, physicochemical properties and α-glucosidase inhibitory activity of polysaccharide from the fruits of wax apple. Carbohydrate Polymers, 2019, 211: 227-236.

14. Ya-Ru Wang, Bao Zhang, Jin-Lei Fan, Qin Yang, Han-Qing Chen*. Effects of sodium tripolyphosphate modification on the structural, functional, and rheological properties of rice glutelin. Food Chemistry, 2019, 281: 18-27.

15. Ying Xie, Meng-Na Li, Han-Qing Chen*, Bao Zhang*. Effects of the combination of repeated heat-moisture treatment and compound enzymes hydrolysis on the structural and physicochemical properties of porous wheat starch. Food Chemistry, 2019, 274: 351-359.

16. Meng-Na Li, Ying Xie, Han-Qing Chen*, Bao Zhang*. Effects of heat-moisture treatment after citric acid esterification on structural properties and digestibility of wheat starch, A- and B-type starch granules. Food Chemistry, 2019, 272: 523-529.

17. Bao Zhang, Bin Bai, Yi Pan, Xiao-Min Li, Jie-Shun Cheng, Han-Qing Chen*. Effects of pectin with different molecular weight on gelatinization behavior, textural properties, retrogradation and in vitro digestibility of corn starch. Food Chemistry, 2018, 264: 58-63.

18. Qing-Qing Lv^#, Gao-Yang Li^#, Qiu-Tao Xie, Bao Zhang*, Xiao-Min Li, Yi Pan, Han-Qing Chen*. Evaluation studies on the combined effect of hydrothermal treatment and octenyl succinylation on the physic-chemical, structural and digestibility characteristics of sweet potato starch. Food Chemistry, 2018, 256: 413-418.

19. Bo Chen, Bao Zhang, Meng-Na Li, Ying Xie, Han-Qing Chen*. Effect of glutenin and gliadin modified by protein-glutaminase on pasting, rheological properties and microstructure of potato starch. Food Chemistry, 2018, 253: 148-155.

20. Bao Zhang, Xiaomin Li, Qiutao Xie, Han Tao*, Wu Wang, Han-Qing Chen*. Preparation and characterization of non-crystalline granular starch and corresponding carboxymethyl starch. International Journal of Biological Macromolecules, 2017, 103: 656-662.

21. Xiao-Pei Hu^#, Bao Zhang^#, Zheng-Yu Jin, Xue-Ming Xu, Han-Qing Chen*. Effect of high hydrostatic pressure and retrogradation treatments on structural and physicochemical properties of waxy wheat starch. Food Chemistry, 2017, 232: 560-565.

22. Da-Nian Zhou^#, Bao Zhang^#, Bo Chen, Han-Qing Chen*. Effects of oligosaccharides on pasting, thermal and rheological properties of sweet potato starch. Food Chemistry, 2017, 230: 516-523.

23. Bao Zhang, Ji-Qiang Mei, Bo Chen, Han-Qing Chen*. Digestibility, physicochemical and structural properties of octenyl succinic anhydride-modified cassava starches with different degree of substitution. Food Chemistry, 2017, 229: 136-141.

24. Bao Zhang, Han Tao, Xiaoli Niu, Sai Li, Han-Qing Chen*. Lysozyme distribution, structural identification, and in vitro release of starch-based microgel-lysozyme complexes. Food Chemistry, 2017, 227: 137-141.

25. Yu-Lu Han^#, Jie Gao^#, Yan-Yan Yin, Zheng-Yu Jin, Xue-Ming Xu, Han-Qing Chen*. Extraction optimization by response surface methodology of mucilage polysaccharide from the peel of Opuntia dillenii haw. fruits and their physicochemical properties. Carbohydrate Polymers, 2016, 151: 381-391.

26. Ting-Ting Huang, Da-Nian Zhou, Zheng-Yu Jin, Xue-Ming Xu, Han-Qing Chen*. Effect of repeated heat-moisture treatments on digestibility, physicochemical and structural properties of sweet potato starch. Food Hydrocolloids, 2016, 54: 202-210.

27. Ji-Qiang Mei, Da-Nian Zhou, Zheng-Yu Jin, Xue-Ming Xu, Han-Qing Chen*. Effects of citric acid esterification on digestibility, structural and physicochemical properties of cassava starch. Food Chemistry, 2015, 187: 378-384.

28. Ting-Ting Huang, Da-Nian Zhou, Zheng-Yu Jin, Xue-Ming Xu, Han-Qing Chen*. Effect of debranching and heat-moisture treatments on structural characteristics and digestibility of sweet potato starch. Food Chemistry, 2015, 187: 218-224.

29. Jie Gao, Yu-Lu Han, Zheng-Yu Jin, Xue-Ming Xu, Xue-Qiang Zha, Han-Qing Chen*, Yan-Yan Yin*. Protective effect of polysaccharides from Opuntia dillenii Haw. fruits on streptozotocin-induced diabetic rats. Carbohydrate Polymers, 2015, 124: 25-34.

30. Xiao-Pei Hu, Ting-Ting Huang, Ji-Qiang Mei, Zheng-Yu Jin, Xue-Ming Xu, Han-Qing Chen*. Effects of continuous and intermittent retrogradation on digestibility and structural properties of waxy wheat starch. Food Chemistry, 2015, 174: 31-36.

31. Jie Gao, Ting Zhang, Zheng-Yu Jin, Xue-Ming Xu, Jun-Hui Wang, Xue-Qiang Zha, Han-Qing Chen*. Structural characterization, physicochemical properties and antioxidant activity of polysaccharide from Lilium lancifolium Thunb. Food Chemistry, 2015, 169: 430-438.

32. Xiao-Pei Hu, Yao-Yu Xie, Zheng-Yu Jin, Xue-Ming Xu, Han-Qing Chen*. Effect of single-, dual-, and triple-retrogradation treatments on in vitro digestibility and structural characteristics of waxy wheat starch. Food Chemistry, 2014, 157: 373-379.

33. Yao-Yu Xie, Xiao-Pei Hu, Zheng-Yu Jin, Xue-Ming Xu, Han-Qing Chen*. Effect of repeated retrogradation on structural characteristics and in vitro digestibility of waxy potato starch. Food Chemistry, 2014, 163: 219-225.

34. Yao-Yu Xie, Xiao-Pei Hu, Zheng-Yu Jin, Xue-Ming Xu, Han-Qing Chen*. Effect of temperature-cycled retrogradation on in vitro digestibility and structural characteristics of waxy potato starch. International Journal of Biological Macromolecules, 2014, 67: 79-84.

35. Ting Zhang, Jie Gao, Zheng-Yu Jin, Xue-Ming Xu, Han-Qing Chen*. Protective effects of polysaccharides from Lilium lancifolium on streptozotocin-induced diabetic mice. International Journal of Biological Macromolecules, 2014, 65: 436-440.

36. Xiao-Ming Chen, Xue-Ming Xu, Zheng-Yu Jin*, Han-Qing Chen*. Expression of an exoinulinase gene from Aspergillus ficuum in Escherichia coli and its characterization. Carbohydrate Polymers, 2013, 92: 1984-1990.

37. Xiao-Ming Chen, Xue-Ming Xu, Zheng-Yu Jin*, Han-Qing Chen*. Expression of an endoinulinase from Aspergillus ficuum JNSP5-06 in Escherichia coli and its characterization. Carbohydrate Polymers, 2012, 88: 748-753. 

38. Han-Qing Chen, Xiao-Ming Chen, Tian-Xiang Chen, Xue-Ming Xu, Zheng-Yu Jin*. Optimization of solid-state medium for the production of inulinase by Aspergillus ficuum JNSP5-06 using response surface methodology. Carbohydrate Polymers, 2011, 86: 249-254.

39. Han-Qing Chen, Xiao-Ming Chen, Tian-Xiang Chen, Xue-Ming Xu, Zheng-Yu Jin*. Extraction optimization of inulinase obtained by solid state fermentation of Aspergillus ficuum JNSP5-06. Carbohydrate Polymers, 2011, 85: 446-451.

40. Han-Qing Chen, Xiao-Ming Chen, Yin Li, Jing Wang, Zheng-Yu Jin*, Xue-Ming Xu, Jian-Wei Zhao, Tian-Xiang Chen, Zheng-Jun Xie. Purification and characterization of exo- and endo-inulinase from Aspergillus ficuum JNSP5-06. Food Chemistry, 2009, 115: 1206-1212.

41. Hai-Xia Xue^#, Hua Kong^#, Yi-Gui Yu, Jing-Wei Zhou, Han-Qing Chen*, Yan-Yan Yin*. Biochanin A protects against angiotensin Ⅱ-induced damage of dopaminergic neurons in rats associated with the increased endophilin A2 expression. Behavioural Pharmacology, 2019, 30: 699-710.

42. Jun Wang^#, Wang-Yang Wu^#, Huan Huang, Wei-Zu Li, Han-Qing Chen*, Yan-Yan Yin*. Biochanin A protects against lipopolysaccharide induced dopaminergic neurons damage both in vivo and in vitro via inhibition of microglia activation. Neurotoxicity Research, 2016, 30: 486-498.

43. Hanqing Chen, Xijin Wang*, Meihua Wang, Liu Yang, Zhiqiang Yan, Yuhong Zhang, Zhenguo Liu. Behavioral and neurochemical deficits in aging rats with increased neonatal iron intake: silibinin’s neuroprotection by maintaining redox balance. Frontiers in Aging Neuroscience, 2015, 7: 206.

44. Jun Wang^#, Can He^#, Wang-Yang Wu, Feng Chen, Yang-Yang Wu, Wei-Zu Li, Han-Qing Chen*, Yan-Yan Yin*. Biochanin A protects dopaminergic neurons against lipopolysaccharide-induced damage and oxidative stress in a rat model of Parkinson’s disease. Pharmacology, Biochemistry and Behavior, 2015, 138: 96-103.

45. Han-Qing Chen, Xi-Jin Wang, Zheng-Yu Jin*, Xue-Ming Xu, Jian-Wei Zhao, Zheng-Jun Xie. Protective effect of isoflavones from Trifolium pratense on dopaminergic neurons. Neuroscience Research, 2008, 62, 123-130.

46. Han-Qing Chen, Zheng-Yu Jin*, Xi-Jin Wang, Xue-Ming Xu, Li Deng, Jian-Wei Zhao. Luteolin protects dopaminergic neurons from inflammation-induced injury through inhibition of microglial activation. Neuroscience Letters, 2008, 448 (2): 175-179.

47. Han-Qing Chen, Zheng-Yu Jin*, Guan-Hong Li. Biochanin A Protects Dopaminergic Neurons against Lipopolysaccharide-induced Damage through Inhibition of Microglia Activation and Proinflammatory Factors Generation. Neuroscience Letters, 2007, 417(2): 112-117.

授权国家发明专利：

1. 陈寒青，高洁，张婷，谢耀宇，胡晓沛. 一种具有降血糖功效的复合果蔬汁饮料. (ZL 201310030088.7) （授权公告日：2014年3月12日）

2. 陈寒青，谢耀宇，胡晓沛，高洁，张婷. 一种生物酶-低温冻融协同制备慢消化小麦淀粉的方法.（ZL 201310058866.3）(授权公告日：2014年8月6日)

科技专著：

1. 金征宇，徐学明，陈寒青，李学红著. 《环糊精化学——制备与应用》（化学工业出版社，2009年第1版）

金征宇，顾正彪，童群义，杨瑞金，徐学明，邓力，陈寒青等编著. 《碳水化合物化学――原理与应用》（化学工业出版社，2008年第1版）

1. 2009年度教育部科学技术进步二等奖

2. 2010年度中国石油和化学工业联合会科技进步二等奖

3. 2011年度中国食品科学技术学会科技创新奖——优秀论文三等奖

4. 2015-2016年度集团公司“三育人”先进个人

其它情况